کد مقاله کد نشریه سال انتشار مقاله انگلیسی ترجمه فارسی نسخه تمام متن
2686788 1564821 2016 6 صفحه PDF سفارش دهید دانلود کنید
عنوان انگلیسی مقاله ISI
Cheese intake lowers plasma cholesterol concentrations without increasing bile acid excretion
ترجمه فارسی عنوان
مصرف پنیر باعث کاهش غلظت کلسترول پلاسما بدون افزایش اسید معده می شود
کلمات کلیدی
لبنیات؛ اسید صفراوی؛ کلسترول؛ قلبی عروقی؛ lipidsCA خون، اسید cholic؛ CDCA، چنوداوکسی کولیک اسید؛ CVD، بیماری قلبی عروقی؛ DCA، اسید دگزیکوشول؛ HDCA، اسید هیودوکسو هیکول؛ HDL، لیپوپروتئین با چگالی بالا؛ LCA، اسید لیتوكوكول LDL، چگالی کم
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی علوم غدد
چکیده انگلیسی

PurposeCheese is a dairy product with high calcium content. It has been suggested that calcium intake may increase fecal excretion of bile acids that would cause a regeneration of bile acids from hepatic cholesterol and thereby result in a lowering of plasma cholesterol concentrations. We aimed to test this hypothesis by assessing bile acid and calcium concentrations in fecal samples from humans after intake of cheese and butter.MethodsThe study was a randomized, 2 × 6 weeks crossover, dietary intervention study including 23 men and women who replaced part of their habitual dietary fat intake with 13% energy from cheese or butter.ResultsAfter 6 weeks of intervention cheese resulted in higher amounts of calcium excreted in feces compared to butter. However, no difference was observed in fecal bile acid output despite lower serum total, LDL and HDL cholesterol concentrations observed with cheese intake.ConclusionWe were not able to confirm the hypothesis that calcium from cheese increases the excretion of fecal bile acids. Therefore, the mechanisms responsible for the lowering of cholesterol concentrations with cheese compared to butter intake remains unresolved.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Nutrition & Intermediary Metabolism - Volume 3, March 2016, Pages 12–17
نویسندگان
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