کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2729753 1147166 2014 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Palliative Sedation in Patients With Advanced Cancer Followed at Home: A Prospective Study
ترجمه فارسی عنوان
سرگیجه تسکین دهنده در بیماران مبتلا به سرطان پیشرفته در خانه: یک مطالعه آینده نگر
کلمات کلیدی
آرامش پایدار، پایان زندگی، مراقبت تسکین دهنده، میدازولام
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی عصب شناسی
چکیده انگلیسی

ContextHome care programs in Italy.ObjectivesThe aim of this study was to assess a protocol for palliative sedation (PS) performed at home.MethodsA total of 219 patients were prospectively assessed to evaluate a PS protocol in patients with advanced cancer followed at home by two home care programs with different territorial facilities. The protocol was based on stepwise administration of midazolam.ResultsA total of 176 of the patients died at home, and PS was performed in 24 of these patients (13.6%). Younger patients received the procedure more frequently than older patients (P = 0.012). The principal reasons to start PS were agitated delirium (n = 20) and dyspnea (n = 4). Mean duration of PS was 42.2 ± 30.4 hours, and the mean doses of midazolam were 23–58 mg/day. Both the home care team and the patients' relatives expressed optimal or good levels of satisfaction with the procedure in all but one case, respectively.ConclusionThis protocol for PS was feasible and effective in minimizing distress for a subgroup of patients who died at home. The characteristics of patients who may be effectively sedated at home should be better explored in future studies.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Pain and Symptom Management - Volume 47, Issue 5, May 2014, Pages 860–866
نویسندگان
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