10 questions fréquentes à propos de la grossesse au cours d'une épilepsie

At the present time, it is assumed that most women with epilepsy could have a successful pregnancy. Nevertheless, pregnancy counselling is mandatory to optimise both maternal and baby outcome. Seizure frequency during pregnancy is highly variable but being seizure free for at least 9 month prior to conception is associated with a high rate of seizure free pregnancy. Regarding the teratogenicity issue, partial seizure occurring during pregnancy appears to be safe whereas generalized seizure should be avoided. Concerning antiepileptic drugs (AED), the most recent data from national and international AED registries regarding major congenital malformation underline that AED polytherapy and valproate de sodium, if possible, should not be used. Moreover, since there is a dose dependant effect for all the AED, low dosages should be prefered. Lastly, breastfeeding should be considered individually.