کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3334312 1213436 2016 13 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Immunoglobulin G4–Related Lymphadenopathy
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی هماتولوژی
پیش نمایش صفحه اول مقاله
Immunoglobulin G4–Related Lymphadenopathy
چکیده انگلیسی

Immunoglobulin G4–related lymphadenopathy (IgG4-RLAD) occurs in the setting of extranodal IgG4-related disease (IgG4-RD), an immune-mediated process described in many organ systems characterized by lymphoplasmacytic infiltrates with abundant IgG4-positive plasma cells and fibrosis. Although the morphologic features in the lymph node sometimes resemble those seen at the extranodal sites, 5 microscopic patterns have been described, most of which resemble reactive lymphoid hyperplasia. This morphologic variability leads to unique diagnostic challenges and a broad differential diagnosis. As IgG4-RD may be exquisitely responsive to steroids or other immunotherapy, histologic recognition and inclusion of IgG4-RLAD in the differential diagnosis is vital.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Surgical Pathology Clinics - Volume 9, Issue 1, March 2016, Pages 117–129
نویسندگان
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