کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3346148 | 1215772 | 2009 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Immune evasion by malaria parasites: a challenge for vaccine development
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ایمونولوژی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Malaria is a deadly infectious disease that affects one to two billion people and kills up to one million children yearly. Despite decades of intensive research, we are still lacking an effective vaccine against malaria. Our efforts are being challenged by the complexity of Plasmodium's life cycle, its ability to parasitize and hide within the host cells, and its masterful ability to avoid clearance by the innate and adaptive host immune responses. In this article we will review the main mechanisms of immune evasion used by malaria parasites and discuss the implications for malaria vaccine development.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Current Opinion in Immunology - Volume 21, Issue 3, June 2009, Pages 321–330
Journal: Current Opinion in Immunology - Volume 21, Issue 3, June 2009, Pages 321–330
نویسندگان
Sofia Casares, Thomas L Richie,