کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4753678 | 1416995 | 2017 | 4 صفحه PDF | دانلود رایگان |
- We report the first complete genome sequence of Streptomyces griseochromogenes.
- S. griseochromogenes ATCC 14511T is a type producer of nucleoside antibiotic.
- S. griseochromogenes ATCC 14511T chromosome consists of 10,764,674Â bp with 9822 protein coding genes.
- 52 gene clusters for the biosynthesis of secondary metabolites were identified using antiSMASH, including four gene clusters of nucleoside antibiotics.
ATCC 14511T (=DSM 40499, =NBRC 13413) is a type strain of Streptomyces griseochromogenes. It is known as a producer of nucleoside antibiotic, blasticidin S. In this report we present the complete genome sequence of S. griseochromogenes ATCC 14511T, which consists of 10,764,674Â bp with a linear chromosome, 9822 protein-coding genes, 6 rRNA operons, 74 tRNA and 3 sRNA. The genomic analysis revealed that 52 putative gene clusters are involved in the biosynthesis of secondary metabolites, including four gene clusters of nucleoside antibiotics. These gene clusters provide a beneficial source for production of bioactive natural compounds.
Journal: Journal of Biotechnology - Volume 249, 10 May 2017, Pages 16-19