کد مقاله کد نشریه سال انتشار مقاله انگلیسی ترجمه فارسی نسخه تمام متن
49276 46731 2016 5 صفحه PDF ندارد دانلود رایگان
عنوان انگلیسی مقاله
A facile, efficacious and reusable Sm2O3/ZrO2 catalyst for the novel synthesis of functionalized 1,4-dihydropyridine derivatives
ترجمه فارسی عنوان
کاتالیزور Sm2O3 / ZrO2 سریع، کارآمد و قابل استفاده مجدد برای سنتز جدید مشتقات 1،4-دی هیدروپوریدین فعال
کلمات کلیدی
سنتز سبز؛ pyridines عاملدار؛ واکنش های چندگانه؛ کاتالیزور ناهمگن؛ بازیافت Sm2O3 / ZrO2؛ کاتالیزور اکسید مخلوط
Green synthesis; Functionalized pyridines; Multicomponent reactions; Heterogeneous catalyst; Recyclability; Sm2O3/ZrO2; Mixed oxide catalyst
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی کاتالیزور
چکیده انگلیسی


• One-pot four-component novel synthesis of eleven functionalized pyridines
• Excellent yields (87 to 96%) at RT in short reaction times (< 20 min)
• Sm2O3/ZrO2 as a superb heterogeneous catalyst
• Easy recovery and reusability of catalyst (7 runs)
• Green solvent/ethanol and cost effective reagents

An efficient four component/one-pot protocol was developed for synthesis of novel functionalized 1,4-dihydropyridines at room temperature by a reaction of malononitrile, substituted aldehydes, dimethylacetylenedicarboxylate and 4-fluoroaniline in ethanol and using Sm2O3/ZrO2 as catalyst. All reactions were completed in < 20 min. The structures of all the new compounds were confirmed by different spectral analyses. The catalyst, Sm2O3/ZrO2 was synthesized and characterized by various techniques including powder X-ray diffraction, N2 adsorption/desorption, scanning electron microscopy, and transmission electron microscopy analysis. The key advantages of this process are good to high yields (87 to 96%), short reaction times, easy work-up, reusability and no chromatographic purification.

Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Catalysis Communications - Volume 79, 5 April 2016, Pages 21–25
نویسندگان
, , , ,