Gold nanoparticles supported on mercaptoethanol directly bonded to MCM-41: An efficient catalyst for the synthesis of propargylamines

Highlight
• Gold nanoparticles supported on MCM-SH.
• Mercaptoethanol directly bonded to MCM-41.
• A3-coupling reaction
• Green A3-coupling reactions with gold heterogeneous catalyst.

Mercaptofunctionalized MCM-41 (MCM-SH) was obtained via reaction of MCM-chloride with mercaptoethanol. Then, gold nanoparticles supported on MCM-SH (Au@HS-MCM nanocomposite) were prepared by chemical reduction of HAuCl4 by NaBH4. The obtained catalyst was used as an effective and reusable heterogeneous catalyst in three-component coupling of aldehydes, alkynes, and amines (A3-coupling) in water. The catalyst could be recovered and reused several times without a significant loss of activity.

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