A novel ratiometric fluorescent probe based on 1, 8-naphthalimide for the detection of Ho3Â + and its bioimaging

Based on the coordination reaction between probe and Ho3+ under mild conditions, we herein report the first ratiometric fluorescent probe which features a rapid signal response time (within 200 s), a good linearity range and a low detection limit (6 × 10− 8M). The potential application of this ratiometric fluorescent probe was demonstrated by fluorescent imaging in living cells.84