Quantification of flupirtine maleate polymorphs using X-ray powder diffraction

An XRPD method for quantifying flupirtine maleate polymorphs was established by systematically optimizing the instrumental parameters and validating the analytical methodology. The calibration curve was found to be a linear fit across the entire range from 0-100% (w/w) with an LoD as low as 0.15% and an LoQ of 0.5%.