Scrupulous recognition of biologically important acids by fluorescent “turn off-on” mechanism of thaicalix reduced silver nanoparticles

Water dispersible silver nanoparticles (AgNps) were prepared using thiacalix[4]arene tetrahydrazide (TCTH) as a reducing and stabilizing agent. TCTH-AgNps were able to effectively reduce the levels of gram-positive bacteria, gram-negative bacteria, and fungi. These properties argue for the potential use of TCTH-AgNps as detectors of histidine and tryptophan and as antibiotics.