Uptake of Ga-curcumin derivatives in different cancer cell lines: Toward the development of new potential 68Ga-labelled curcuminoids-based radiotracers for tumour imaging

The biological behavior of three Ga-curcuminoid complexes is studied in vitro in order to develop new radiopharmaceuticals labelled with gallium-68. Their uptake, internalization, efflux, and affinity is tested on different types of cells lines, hinting a possible application of these compounds as future radiotracers for cancer.113