Structure-activity relationship between Zn2Â +-chelated alkylated poly(1-vinylimidazole) and gene transfection

Ethylated PVIm (PVIm-Et) chelated the highest amount of Zn2 + ions, as compared with methylated or butylated PVIm, resulting in stable polyion complexes to deliver the highest amount of the Zn2 + ions inside the cell and to leading to the highest gene transfection.211