کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5156711 | 1500586 | 2017 | 27 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Polysaccharides with immunomodulating activity from roots of Gentiana crassicaulis
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کلمات کلیدی
d-Xylose (PubChem CID: 135191)d-Mannose (PubChem CID: 18950)l-Rhamnose (PubChem CID: 25310)D-glucuronic acid (PubChem CID: 94715)d-Fructose (PubChem CID: 5984)d-Galacturonic acid (PubChem CID: 439215)D-galactose (PubChem CID: 6036) - D-گالاکتوز (PubChem CID: 6036)d-Glucose (PubChem CID: 5793) - D-گلوکز (PubChem CID: 5793)Trifluoroacetic acid (PubChem CID: 6422) - اسید Trifluoroacetic (PubChem CID: 6422)Complement system - دستگاه کمپلمان، سیستم کمپلمانPurification - پاکسازیPolysaccharides - پلیساکاریدها
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Two polysaccharides, GCP-I-I and GCP-II-I, were obtained from 100 °C water extracts of Gentiana crassicaulis roots by DEAE anion exchange chromatography and gel filtration. The results from methanolysis, methylation, FT-IR and NMR, indicated that these two fractions are typical pectic polysaccharides, with HG and RG-I regions and AG-I/AG-II side chains, and some of the galacturonic acid units of fraction GCP-I-I were methyl esterified. Fractions GCP-I-I and GCP-II-I, both exhibited potent complement fixation, and fraction GCP-I-I was more potent than positive control BPII. The higher complement fixation activity obtained in fraction GCP-I-I may be due to the higher Mw and/or higher amount of AG-II present in fraction GCP-I-I than fraction GCP-II-I. The polysaccharides from G. crassicaulis could be used as a potential natural immunomodulator.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Carbohydrate Polymers - Volume 172, 15 September 2017, Pages 306-314
Journal: Carbohydrate Polymers - Volume 172, 15 September 2017, Pages 306-314
نویسندگان
Yuan-Feng Zou, Yu-Ping Fu, Xing-Fu Chen, Ingvild Austarheim, Kari Tvete Inngjerdingen, Chao Huang, Fei-Yi Lei, Xu Song, Lixia Li, Gang Ye, Lemlem Dugassa Eticha, Zhongqiong Yin, Berit Smestad Paulsen,