One strain-many compounds (OSMAC) method for production of polyketides, azaphilones, and an isochromanone using the endophytic fungus Dothideomycete sp.

Polyketides (1-3), an isochromanone 4, and azaphilone 5 and 6 are produced by one strain-many compounds (OSMAC) approach. Metabolite production of the fungus Dothideomycete sp. depends on culture media and source of potato and malt extracts used for the preparation of media.75