Benzopyrans from Curvularia sp., an endophytic fungus associated with Ocotea corymbosa (Lauraceae)

Benzopyrans (2) and (4) were produced by an endophytic fungus Curvularia sp. associated to Ocotea corymbosa, a native plant of Brazilian Cerrado. The structures of the derivatives were established on the basis of comprehensive spectroscopic analysis, mainly using 1D and 2D NMR experiments. Analyses of biological activities were carried out on a human cervix tumor cell line aimed at evaluation of potential effects on a mammalian cell line proliferation. Only 2 showed a significant activity.