کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5175812 | 1502434 | 2017 | 4 صفحه PDF | دانلود رایگان |
- Four new compounds were isolated from the Clausena dunniana var. robusta.
- These new compounds were named as clausenaglycosides A-âD.
- Fourteen known compounds were also isolated from this plant.
- Their absolute configurations were determined by NMR analyses and CD data.
- All isolated compounds were evaluated for their anti-inflammatory activities.
Four new phenylpropanoid glycosides, clausenaglycosides A-D (1-4), along with fourteen known compounds (5-18) were isolated from the leaves and twigs of Clausena dunniana var. robusta. The structures of the isolated compounds were determined by a combination of 1D and 2D NMR, MS, and CD spectroscopic data. The NF-κB inhibitory activity was evaluated in HeLa cells. Compound 17 displayed a moderate inhibition against NF-κB activation.
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Journal: Phytochemistry Letters - Volume 22, December 2017, Pages 138-141