Assessing the phytochemical profiles and antidepressant-like activity of four Peruvian Hypericum species using the murine forced swimming test

- Crude extracts of Peruvian Hypericum spp. exhibited antidepressant-like activity.
- These extracts were analyzed by TLC, HPLC-DAD and UPLC-DAD/Q-TOF-MS.
- The extracts were rich in flavonoids, principally hyperoside.
- Dimeric acylphloroglucinols were minor components of the extracts.