α-Glucosidase inhibitory constituents from Chrozophora plicata

The methanolic extract of Chrozophora plicata yielded five new (1-5), together with seven known compounds (6-12). Their structures were established by using 1D and 2D NMR spectroscopy and mass spectrometry. Compounds 1-12 were evaluated for their α-glucosidase inhibitory activity and 4 found potent inhibitor with IC50 value 27.8 μM.