کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5218035 | 1383314 | 2013 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Three-component synthesis of 2-amino-3-cyano-5-oxo-4-perfluoroalkyl-5,6,7,8-tetrahydro-4H-chromene derivatives
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موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
A variety of 2-amino-3-cyano-5-oxo-4-perfluoroalkyl-5,6,7,8-tetrahydro-4H-chromene derivatives were achieved via a one-pot, three-component reaction from easily available methyl 2-perfluoroalkynoate, malononitrile (or ethyl cyanoacetate), and diverse cyclic 1,3-diketones. Moderate to good yields (up to 93%) were obtained in the presence of catalytic methylamine. This process went through a tandem Michael addition–cyclization reaction and was mild and easily performed.
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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron - Volume 69, Issue 30, 29 July 2013, Pages 6121–6128
Journal: Tetrahedron - Volume 69, Issue 30, 29 July 2013, Pages 6121–6128