Ce(OTf)3-catalyzed multicomponent domino cyclization-aromatization of ferrocenylacetylene, aldehydes, and amines: a straightforward synthesis of ferrocene-containing quinolines

A straightforward and economic method for the synthesis of ferrocene-containing quinolines by the Ce(OTf)3-catalyed one-pot three-component domino cyclization/aromatization reaction of ferrocenylacetylene, aldehydes, and amines under an air atmosphere was developed. A series of ferrocene substituted quinolines have been synthesized from simple and readily available starting materials in good yields.