A facile and efficient synthesis of fully substituted pyridin-2(1H)-ones from α-oxoketene-S,S-acetals

A facile and efficient synthesis of fully substituted pyridin-2(1H)-ones has been developed by the reaction of readily available α-oxoketene-S,S-acetals with malononitrile in the presence of sodium methoxide in methanol under reflux.

Figure optionsDownload as PowerPoint slide