Reactions of 2-alkylimidazoles and 2-methylbenzimidazoles with 1,3-diacid chlorides. Synthesis of highly functionalized hetero-cycles under mild conditions

Highly functionalized heterocycles were synthesized in one-pot reactions of 2-alkylimidazoles or 2-methylbenzimidazoles with 1,3-diacid chlorides. Some of the cyclizations proceed through cyclic-N,N′-ketene acetal intermediates.

Highly functionalized heterocycles were synthesized in one-pot reactions of 2-alkylimidazoles or 2-methylbenzimidazoles with 1,3-diacid chlorides. Some of the cyclizations proceed through cyclic-N,N′-ketene acetal intermediates.