کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5274210 | 1385506 | 2008 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Synthesis and conformational analysis of benzimidazole-based reverse turn mimics
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موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
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چکیده انگلیسی
New benzimidazole-based tetrapeptide mimics were synthesized and their conformational features were studied by NMR and molecular modeling techniques. All the analyses led to the conclusion that a β-turn is stabilized in both 2 and 3. Since values of the torsion angles do not allow an univocal definition of the β-turn type, structures 2 and 3 could be assigned to the generic type IV classification.
New benzimidazole-based tetrapeptide mimics were synthesized and their conformational features were studied by NMR and molecular modeling techniques. All the analyses led to the conclusion that a β-turn is stabilized in both 2 and 3.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron Letters - Volume 49, Issue 8, 18 February 2008, Pages 1293-1296
Journal: Tetrahedron Letters - Volume 49, Issue 8, 18 February 2008, Pages 1293-1296
نویسندگان
Giordano Lesma, Alessandro Sacchetti, Alessandra Silvani,