کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5370618 1503891 2017 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Broadband diffuse optical characterization of elastin for biomedical applications
ترجمه فارسی عنوان
مشخصات اپتیکال پلاسمای الاستین برای کاربردهای بیومدیکال
کلمات کلیدی
طیف سنجی زمان حل، اپتیک بیومدیکال، الاستین، جذب، پراکندگی، اپتیکهای متنوع کلاژن، نزدیک به طیف سنجی مادون قرمز،
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی تئوریک و عملی
چکیده انگلیسی


- Broadband 550-1350 nm optical characterization of elastin was presented.
- Absorption was accurately estimated by effectively eliminating the contamination of scattering and fluorescence by optimal use of time domain diffuse optical spectroscopy, bandpass filters and diffusion models.
- A brief comparison between collagen and elastin was presented, highlighting similarities and key regions to distinguish.

Elastin is a key structural protein of dynamic connective tissues widely found in the extracellular matrix of skin, arteries, lungs and ligaments. It is responsible for a range of diseases related to aging of biological tissues. The optical characterization of elastin can open new opportunities for its investigation in biomedical studies. In this work, we present the absorption spectra of elastin using a broadband (550-1350 nm) diffuse optical spectrometer. Distortions caused by fluorescence and finite bandwidth of the laser source on estimated absorption were effectively accounted for in measurements and data analysis and compensated. A comprehensive summary and comparison between collagen and elastin is presented, highlighting distinct features for its accurate quantification in biological applications.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biophysical Chemistry - Volume 229, October 2017, Pages 130-134
نویسندگان
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