Non-linear longitudinal compression effect on dynamics of the transcription bubble in DNA

- A two-component model of DNA is studied.
- Dynamics of the transcription bubble.
- Non-linear longitudinal compression.

The dependence of the dynamics of transcription bubble on the parameters of non-linear longitudinal compression is presented on the base of simple model of soliton-like conformational switchings in two-component bistable polymer molecules with energetically non-equivalent stable states. It has been shown that under certain conditions the longitudinal compression may be a trap for a conformational switching.