Characteristic of peroxyoxalate-chemiluminescence intensity in the presence of Chlorpheniramine maleate and its analytical application

► The present study convincingly shows the enhancement of chemiluminescence intensity of peroxyoxalte chemiluminescence system (TCPO- H2O2- sodium salicylate- fluorescer) in the presence of chlorpheniramine maleate. ► Results also introduced a reliable method for determination of chlorpheniramine using peroxyoxalte chemiluminescence system. ► A pooled-intermediate model was used for determination the kinetics parameters of chemiluminescence with and without chlorpheniramine maleate. ► Results also specified that there is a linear relationship between chlorpheniramine maleate concentration and chemiluminescence intensity.