Oxidative degradation of norfloxacin by a lipophilic oxidant, cetyltrimethylammonium permanganate in water-acetonitrile medium: A kinetic and mechanistic study

The rate of the oxidation of norfloxacin by CTAP in acetonitrile-water binary solvent mixture is primarily controlled by the preferential solvation of reactant and the transition state through specific and nonspecific solute-solvent interaction.