کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5434037 1398083 2016 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Light activated liposomes: Functionality and prospects in ocular drug delivery
ترجمه فارسی عنوان
لیپوزوم های فعال نور: عملکرد و چشم انداز در تحویل دارو چشم
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه مهندسی مواد بیومتریال
چکیده انگلیسی

Ocular drug delivery, especially to the retina and choroid, is a major challenge in drug development. Liposome technology may be useful in ophthalmology in enabling new routes of delivery, prolongation of drug action and intracellular drug delivery, but drug release from the liposomes should be controlled. For that purpose, light activation may be an approach to release drug at specified time and site in the eye. Technical advances have been made in the field of light activated drug release, particularly indocyanine green loaded liposomes are a promising approach with safe materials and effective light triggered release of small and large molecules. This review discusses the liposomal drug delivery with light activated systems in the context of ophthalmic drug delivery challenges.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Controlled Release - Volume 244, Part B, 28 December 2016, Pages 157-166
نویسندگان
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