کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5434244 1509140 2017 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Design and fabrication of auxetic PCL nanofiber membranes for biomedical applications
موضوعات مرتبط
مهندسی و علوم پایه مهندسی مواد بیومتریال
پیش نمایش صفحه اول مقاله
Design and fabrication of auxetic PCL nanofiber membranes for biomedical applications
چکیده انگلیسی


- This paper reports state-of-the-art method for fabrication of auxetic polycaprolactone (PCL) based nanofiber membranes.
- The auxetic PCL nanofiber membranes shows 10-fold increase in their elongation capacity than the conventional PCL nanofibers
- Auxetic nanofiber membranes show tunable mechanical and deformation properties suitable for variousbiomedical applications.

The main objective of this study was to fabricate poly (ε-caprolactone) (PCL)-based auxetic nanofiber membranes and characterize them for their mechanical and physicochemical properties. As a first step, the PCL nanofibers were fabricated by electrospinning with two different thicknesses of 40 μm (called PCL thin membrane) and 180 μm (called PCL thick membrane). In the second step, they were tailored into auxetic patterns using femtosecond laser cut technique. The physicochemical and mechanical properties of the auxetic nanofiber membranes were studied and compared with the conventional electrospun PCL nanofibers (non-auxetic nanofiber membranes) as a control. The results showed that there were no significant changes observed among them in terms of their chemical functionality and thermal property. However, there was a notable difference observed in the mechanical properties. For instance, the thin auxetic nanofiber membrane showed the magnitude of elongation almost ten times higher than the control, which clearly demonstrates the high flexibility of auxetic nanofiber membranes. This is because that the auxetic nanofiber membranes have lesser rigidity than the control nanofibers under the same load which could be due to the rotational motion of the auxetic structures. The major finding of this study is that the auxetic PCL nanofiber membranes are highly flexible (10-fold higher elongation capacity than the conventional PCL nanofibers) and have tunable mechanical properties. Therefore, the auxetic PCL nanofiber membranes may serve as a potent material in various biomedical applications, in particular, tissue engineering where scaffolds with mechanical cues play a major role.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Materials Science and Engineering: C - Volume 81, 1 December 2017, Pages 334-340
نویسندگان
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