کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5434330 1509141 2017 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Electrospinning of gelatin with tunable fiber morphology from round to flat/ribbon
موضوعات مرتبط
مهندسی و علوم پایه مهندسی مواد بیومتریال
پیش نمایش صفحه اول مقاله
Electrospinning of gelatin with tunable fiber morphology from round to flat/ribbon
چکیده انگلیسی


- Gelatin fibers with round and flat/ribbon morphology were produced via electrospinning.
- Flat/ribbon gelatin fibers were obtained at high voltages and gelatin concentrations.
- The gelatin fibers were cross-linked with TDI linker in acetone/pyridine solution.
- The cross-linking of the gelatin fibers led to substantial changes on the fiber texture.

The electrospinning of gelatin with tunable fiber morphology from round to flat/ribbon was shown, and the detailed studies were conducted to correlate the fiber morphology with electrospinning process parameters and gelatin concentration in electrospinning solution. Particularly, variations in the applied voltage and the concentration of gelatin led to the transition of fiber shape from round to flat/ribbon. The formation of flat-shaped fibers was attributed to rapid evaporation of the solvent (formic acid) from the fiber matrix with increasing the applied voltage and gelatin concentration. On the other hand, round fibers were due to the steady evaporation of formic acid throughout the cross-section of fibers. WAXS analysis revealed that the loss of triple-helical crystalline structure in gelatin after the electrospinning process. The gelatin fibers were cross-linked through treatment with toluene 2,4-diisocyanate (TDI) in a mixed solution of acetone and pyridine, and XPS confirmed the cross-linking of the fibers over an increased carbon content on the elemental composition of the fiber surface due to the incorporated TDI moieties. Overall, this study focuses on morphological tuning of gelatin electrospun fibers towards a flat/ribbon-like structure by variation of electrospinning parameters and polymer concentration, and thus, the proposed concept can be adapted towards flattened/ribbon-like fibers of other protein-based systems by electrospinning.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Materials Science and Engineering: C - Volume 80, 1 November 2017, Pages 371-378
نویسندگان
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