کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5434598 1509150 2017 15 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Liposome-based drug co-delivery systems in cancer cells
ترجمه فارسی عنوان
سیستم های همکاری با داروهای مبتنی بر لیپوزوم در سلول های سرطانی
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه مهندسی مواد بیومتریال
چکیده انگلیسی


- This paper focuses on the recent advances of cancer drug delivery systems employing liposomal co-delivery chemotherapy.
- Liposomal-based combination chemotherapy strategies include.
- Different liposomal-based combination chemotherapy strategies are discussed.
- In vitro, in vivo and clinical researches of liposomal co-drug delivery systems in cancer treatment are reviewed.
- Liposomal drug delivery Challenges are mentioned.

Combination therapy and nanotechnology offer a promising therapeutic method in cancer treatment. By improving drug's pharmacokinetics, nanoparticulate systems increase the drug's therapeutic effects while decreasing its adverse side effects related to high dosage. Liposomes are extensively used as drug delivery systems and several liposomal nanomedicines have been approved for clinical applications. In this regard, liposome-based combination chemotherapy (LCC) opens a novel avenue in drug delivery research and has increasingly become a significant approach in clinical cancer treatment. This review paper focuses on LCC strategies including co-delivery of: two chemotherapeutic drugs, chemotherapeutic agent with anti-cancer metals, and chemotherapeutic agent with gene agents and ligand-targeted liposome for co-delivery of chemotherapeutic agents. Definitely, the multidisciplinary method may help improve the efficacy of cancer therapy. An extensive literature review was performed mainly using PubMed.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Materials Science and Engineering: C - Volume 71, 1 February 2017, Pages 1327-1341
نویسندگان
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