کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5498166 | 1399970 | 2017 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Dosimetric effect of multileaf collimator leaf width on volumetric modulated arc stereotactic radiotherapy for spine tumors
ترجمه فارسی عنوان
اثر دوزیمتری عرض برگ کولیماتور چند برگه بر روی پرتو تراپی سترونوتاکتیک مدولاسیون تابشی برای تومورهای ستون فقرات
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موضوعات مرتبط
مهندسی و علوم پایه
فیزیک و نجوم
تشعشع
چکیده انگلیسی
This work aimed to study the dosimetric effect of multileaf collimator (MLC) leaf widths in treatment plans for patients receiving volumetric modulated arc therapy (VMAT) for spine stereotactic body radiation therapy (SBRT). Thirteen patients treated with spine SBRT were retrospectively selected for this study. The patients were treated following the protocol of the Radiation Therapy Oncology Group 0631 (RTOG 0631) for spine metastasis. The prescription dose was 16âGy in 1 fraction to 90% of the target volume (V16â>â90%). The maximum spinal cord dose of 14âGy and 10% of the spinal cord receivingâ<â10âGy (V10) were the acceptable tolerance doses. For the purpose of this study, 2 dual-arc VMAT plans were created for each patient using 3 different MLC leaf widths: 2.5âmm, 4âmm, and 5âmm. The compliance with the RTOG 0631 protocol, conformity index (CI), dose gradient index (DGI), and number of monitor units (MUs) were compared. The average V16Gy of the targets was 91.8â±â1.2%, 92.2â±â2.1%, and 91.7â±â2.3% for 2.5-mm, 4-mm, and 5-mm leaf widths, respectively (pâ=â0.78). Accordingly, the average CI was 1.45â±â0.4, 1.47â±â0.29, and 1.47â±â0.31 (pâ=â0.98), respectively. The average DGI was 0.22â±â0.04, 0.20â±â0.06, and 0.22â±â0.05, respectively (pâ=â0.77). The average maximum dose to the spinal cord was 12.45â±â1.0âGy, 12.80â±â1.0âGy, and 12.48â±â1.1 (pâ=â0.62) and V10% of the spinal cord was 3.6â±â2.1%, 5.6â±â2.8%, and 5.5â±â3.0% (pâ=â0.11) for 2.5-mm, 4-mm, and 5-mm leaf widths, respectively. Accordingly, the average number of MUs was 4341â±â500 MU, 5019â±â834 MU, and 4606â±â691 MU, respectively (pâ=â0.053). The use of 2.5-mm, 4-mm, and 5-mm MLCs achieved similar VMAT plan quality as recommended by the RTOG 0631. The dosimetric parameters were also comparable for the 3 MLCs. In general, any of these leaf widths can be used for spine SBRT using VMAT.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Medical Dosimetry - Volume 42, Issue 2, Summer 2017, Pages 111-115
Journal: Medical Dosimetry - Volume 42, Issue 2, Summer 2017, Pages 111-115
نویسندگان
Ahmad Ph.D., Huang Ph.D., Laxmi M.S., Peng Ph.D., Toufik Ph.D., Ping Ph.D.,