کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5518205 1543915 2017 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Genomics/technical resourcesMetabolism of branched-chain amino acids revealed by transcriptome analysis in Vibrio alginolyticus
موضوعات مرتبط
مهندسی و علوم پایه علوم زمین و سیارات علوم زمین و سیاره ای (عمومی)
پیش نمایش صفحه اول مقاله
Genomics/technical resourcesMetabolism of branched-chain amino acids revealed by transcriptome analysis in Vibrio alginolyticus
چکیده انگلیسی

Branched-chain amino acids (BCAAs) play important roles in nitrogen metabolism. However, little is known about the metabolism of BCAAs in the fish pathogen Vibrio alginolyticus. In this study, the global gene expression patterns of V. alginolyticus ZJ-T cultured in M63 minimal medium supplemented with ammonium sulfate or with three BCAAs (isoleucine, leucine and valine) as nitrogen source were evaluated by transcriptome analysis. The results revealed that 311 genes are up-regulated (| log2(Fold Change)| > 1), which are involved in the pathways of flagellar assembly, bacterial chemotaxis and oxidative phosphorylation etc, and meanwhile 251 genes are down-regulated, which are involved in the pathways of BCAAs biosynthesis, selenocompound metabolism and C5-branced dibasic acid metabolism etc. This study contributes to the understanding of the BCAAs metabolism in the Vibrios.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Marine Genomics - Volume 35, October 2017, Pages 23-26
نویسندگان
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