|کد مقاله||کد نشریه||سال انتشار||مقاله انگلیسی||ترجمه فارسی||نسخه تمام متن|
|5519188||1401111||2017||4 صفحه PDF||ندارد||دانلود کنید|
â¢The venoms of CrotalusÂ durissus cumanensis, were different. The juvenilesâ venom has a fasterÂ blockade than adultsâ venom.â¢The juvenilesâ venomÂ did not inhibit significantly the ACh and KCl agonistsâ response, the venomÂ from adults did.â¢The juvenilesâ venomÂ has a more neurotoxic effect than myotoxic, on the contrary to the venom fromÂ adults.
A toxinological study was performed to compare the neuromuscular effect of venom from adult and juvenile specimens from Crotalus durissus cumanensis from Guajira, Colombia. Both venoms exhibited neurotoxic activity in chick biventer cervicis nerve-muscle preparation. In addition, venom from juveniles was faster than adults to produce a neuromuscular blockade. In the contrary to the venom from juvenile's, at high doses, adult's venom affected the ACh and KCl contractures, indicating a myotoxic effect.
Journal: Toxicon - Volume 139, 1 December 2017, Pages 41-44