کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5519224 | 1544098 | 2017 | 5 صفحه PDF | دانلود رایگان |
- A Crotoxin-like neurotoxin was identified in Crotalus lepidus klauberi venom from Aguascalientes, Mexico.
- Venoms containing Crotoxin-like neurotoxin have a significantly lower LD50 than the other studied venoms.
- Venom from intergrade Crotalus lepidus x aquilus showed significant differences, particularly regarding lethality.
The venoms from two species of rock rattlesnakes and an intergrade population were studied. Differences were noted in SDS-PAGE and RP-HPLC profiles and only the venom from the intergrade population showed low procoagulant activity. Also, a Crotoxin-like neurotoxic PLA2 was identified in the venom of C. l. klauberi, the most toxic of the analyzed venoms. This is the first report of such a toxin in C. l. klauberi from Aguascalientes, Mexico.
Journal: Toxicon - Volume 138, November 2017, Pages 191-195