|کد مقاله||کد نشریه||سال انتشار||مقاله انگلیسی||ترجمه فارسی||نسخه تمام متن|
|5529501||1401700||2017||6 صفحه PDF||سفارش دهید||دانلود کنید|
Background and purposeThe reliability of post-implant dosimetry in the OR depends on the geometrical variability of implant and anatomy after the procedure. The purpose was to gain detailed information on seed displacement patterns in different sectors of the prostate.Materials and methodsOf 33 patients with stranded seed implants the seed geometry and the dose distribution were compared between the situation in the OR just after the procedure, based on ultrasound images, and the situation after 1Â month, based on registered CT and MR images.ResultsThere was a substantial displacement of ventral seeds of 3.8Â Â±Â 2.5Â mm in caudal direction (pÂ <Â 0.001). Of these ventral seeds cranially located seeds moved more than caudally located seeds, 4.5Â Â±Â 2.7Â mm and 2.9Â Â±Â 2.6Â mm, respectively (pÂ <Â 0.001). The D90 in the dorsal-caudal and ventral-caudal sectors increased with respectively 44Â Â±Â 20Â Gy and 29Â Â±Â 28Â Gy (pÂ <Â 0.001) and decreased with 17Â Â±Â 31Â Gy in the ventral-cranial sector (pÂ =Â 0.008).ConclusionsThere were substantial changes in dose distribution 1Â month after the procedure, mainly due to implant and prostate shrinkage and displacement of ventral seed strands in caudal direction. When performing dynamic dosimetry or dosimetry at the end of the procedure the effect of these phenomena has to be taken into account when using stranded seeds.
Journal: Radiotherapy and Oncology - Volume 124, Issue 1, July 2017, Pages 68-73