کد مقاله کد نشریه سال انتشار مقاله انگلیسی ترجمه فارسی نسخه تمام متن
5529501 1401700 2017 6 صفحه PDF سفارش دهید دانلود کنید
عنوان انگلیسی مقاله ISI
Prostate brachytherapyDisplacement patterns of stranded I-125 seeds after permanent brachytherapy of the prostate: Dosimetry in the operating room put into perspective
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موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی تحقیقات سرطان
پیش نمایش صفحه اول مقاله
Prostate brachytherapyDisplacement patterns of stranded I-125 seeds after permanent brachytherapy of the prostate: Dosimetry in the operating room put into perspective
چکیده انگلیسی

Background and purposeThe reliability of post-implant dosimetry in the OR depends on the geometrical variability of implant and anatomy after the procedure. The purpose was to gain detailed information on seed displacement patterns in different sectors of the prostate.Materials and methodsOf 33 patients with stranded seed implants the seed geometry and the dose distribution were compared between the situation in the OR just after the procedure, based on ultrasound images, and the situation after 1 month, based on registered CT and MR images.ResultsThere was a substantial displacement of ventral seeds of 3.8 ± 2.5 mm in caudal direction (p < 0.001). Of these ventral seeds cranially located seeds moved more than caudally located seeds, 4.5 ± 2.7 mm and 2.9 ± 2.6 mm, respectively (p < 0.001). The D90 in the dorsal-caudal and ventral-caudal sectors increased with respectively 44 ± 20 Gy and 29 ± 28 Gy (p < 0.001) and decreased with 17 ± 31 Gy in the ventral-cranial sector (p = 0.008).ConclusionsThere were substantial changes in dose distribution 1 month after the procedure, mainly due to implant and prostate shrinkage and displacement of ventral seed strands in caudal direction. When performing dynamic dosimetry or dosimetry at the end of the procedure the effect of these phenomena has to be taken into account when using stranded seeds.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Radiotherapy and Oncology - Volume 124, Issue 1, July 2017, Pages 68-73
نویسندگان
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