کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5555112 1559627 2017 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
C21 steroidal glycosides and oligosaccharides from the root bark of Periploca sepium
موضوعات مرتبط
علوم پزشکی و سلامت داروسازی، سم شناسی و علوم دارویی داروشناسی
پیش نمایش صفحه اول مقاله
C21 steroidal glycosides and oligosaccharides from the root bark of Periploca sepium
چکیده انگلیسی

Four new C21 steroidal glycosides (1-4), named perisepiumosides FI (1-4) together with six known steroidal glycosides (5-10) and four oligosaccharides (11-14), were isolated from the root bark of Periploca sepium. Their structures were characterized on the basis of 1D and 2D-NMR spectroscopic data as well as HR-ESI-MS analysis. The evaluation of inhibition activity against human A-549 and HepG2 cell lines indicated that compounds 2, 8, 10 and 13 showed different levels of cytotoxic activities with IC50 values ranging from 0.61 to 7.86 μM.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Fitoterapia - Volume 118, April 2017, Pages 6-12
نویسندگان
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