The role of innate lymphoid cells in healthy and inflamed skin

- This review describes recent findings of the role of ILC in healthy skin.
- This review discusses the role of ILC in atopic dermatitis and the correlation between ILC and lack of filaggrin.
- This review discusses the role of ILC in psoriasis and allergic contact dermatitis.

The skin constitutes the interface between the organism and the environment, and it protects the body from harmful substances in the environment via physical, chemical and immunological barriers. The immunological barrier of the skin comprises both cells from the innate and the adaptive immune system. During the last years, it has become clear that innate lymphoid cells play a role in homeostasis and inflammation of the skin in humans and mice. In this review, we will discuss the role of innate lymphoid cells in healthy and inflamed skin with special focus on their role in atopic dermatitis.