کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5671386 | 1592819 | 2017 | 6 صفحه PDF | دانلود رایگان |
- There is increasing evidence of the efficacy of probiotics in primary prevention of CDI.
- Only three probiotics have been studied for CDI activity: BioK+, Lactobacillus rhamnosus GG and Saccharomyces boulardii.
- The value of probiotics in CDI is confused from combining primary & secondary prophylaxis, & different strains into pooled analyses.
The role of probiotics as adjunctive measures in the prevention of Clostridium difficile infection (CDI) has been controversial. However, a growing body of evidence has suggested that they have a role in primary prevention of CDI. Elements of this controversy are reviewed and the proposed mechanisms of action, the value and cost effectiveness of probiotics are addressed with a focus on three agents, Saccharomyces boulardii, Lactobacillus rhamnosus GG and the combination of Lactobacillus acidophilus CL1285, Lactobacillus casei LBC80R, Lactobacillus rhamnosus CLR2 (Bio-K+).
Journal: Anaerobe - Volume 45, June 2017, Pages 114-119