Potenciación con carbamazepina en la depresión mayor resistente. A propósito de un caso clínico

Depression is a relatively common mental disorder, and it often becomes debilitating for the sufferer. In these cases antidepressant drug therapy is essential for its remission. In some cases, augmentation with non-antidepressant drugs can be an alternative, with very good results in clinical practice. The following case concerns a patient of 48 years, referred by her Primary Care doctor, due to presenting with a major depressive disorder of several months onset. As there was an unsatisfactory response after having been prescribed several antidepressants, including some in combination, it was decided to admit to hospital Augmentation treatment with carbamazepine and sertraline was decided by the Psychiatric Department. An improvement was observed at first, followed by complete remission of depression within a few weeks. After several months of follow-up, she has not relapsed, and no side effects were reported.