کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5756389 | 1622549 | 2017 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Methyl mercury, but not inorganic mercury, associated with higher blood pressure during pregnancy
ترجمه فارسی عنوان
جیوه متیل، اما نه جیوه معدنی، همراه با فشار خون بالا در دوران بارداری
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کلمات کلیدی
EPAEthyl mercuryThreeICP-DRC-MSIHGMeHgCDCDBPSBPUS EPA - EPA ایالات متحدهTHg - THGUnited States Environmental Protection Agency - آژانس حفاظت از محیط زیست ایالات متحدهEicosapentaenoic acid - اسید ایکوزاپنتانوئیکdocosahexaenoic acid - اسید داکوزاگزوائونیکPregnancy - بارداریMethylmercury compounds - ترکیبات متیل کرچریnot detected - تشخیص داده نشدMercury - جیوهMethyl mercury - جیوه متیلInorganic mercury - جیوه معدنیLOD یا Limit of detection - حد تشخیصDHA - دوکوساهگزائنوئیک اسیدbody mass index - شاخص توده بدنBMI - شاخص توده بدنیinductively coupled plasma mass spectrometry - طیفسنجی جرمی پلاسمای جفتشده القاییICP-MS - طیفسنجی جرمی پلاسمای جفتشده القاییconfidence interval - فاصله اطمینانdiastolic blood pressure - فشار خون دیاستولیکsystolic blood pressure - فشار خون سیستولیکPulse pressure - فشار نبضBlood pressure - فشارخونlimit of detection - محدودیت تشخیصUnited States Centers for Disease Control and Prevention - مراکز ایالات متحده برای کنترل و پیشگیری از بیماری هاTotal mercury - کل جیوه
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم محیط زیست
بهداشت، سم شناسی و جهش زایی
چکیده انگلیسی
Prior studies addressing associations between mercury and blood pressure have produced inconsistent findings; some of this may result from measuring total instead of speciated mercury. This cross-sectional study of 263 pregnant women assessed total mercury, speciated mercury, selenium, and n-3 polyunsaturated fatty acids in umbilical cord blood and blood pressure during labor and delivery. Models with a) total mercury or b) methyl and inorganic mercury were evaluated. Regression models adjusted for maternal age, race/ethnicity, prepregnancy body mass index, neighborhood income, parity, smoking, n-3 fatty acids and selenium. Geometric mean total, methyl, and inorganic mercury concentrations were 1.40 µg/L (95% confidence interval: 1.29, 1.52); 0.95 µg/L (0.84, 1.07); and 0.13 µg/L (0.10, 0.17), respectively. Elevated systolic BP, diastolic BP, and pulse pressure were found, respectively, in 11.4%, 6.8%, and 19.8% of mothers. In adjusted multivariable models, a one-tertile increase of methyl mercury was associated with 2.83 mmHg (0.17, 5.50) higher systolic blood pressure and 2.99 mmHg (0.91, 5.08) higher pulse pressure. In the same models, an increase of one tertile of inorganic mercury was associated with â1.18 mmHg (â3.72, 1.35) lower systolic blood pressure and â2.51 mmHg (â4.49, â0.53) lower pulse pressure. No associations were observed with diastolic pressure. There was a non-significant trend of higher total mercury with higher systolic blood pressure. We observed a significant association of higher methyl mercury with higher systolic and pulse pressure, yet higher inorganic mercury was significantly associated with lower pulse pressure. These results should be confirmed with larger, longitudinal studies.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Environmental Research - Volume 154, April 2017, Pages 247-252
Journal: Environmental Research - Volume 154, April 2017, Pages 247-252
نویسندگان
Ellen M. Wells, Julie B. Herbstman, Yu Hong Lin, Joseph R. Hibbeln, Rolf U. Halden, Frank R. Witter, Lynn R. Goldman,