Evaluation on the generative mechanism and biological toxicity of microcystin-LR disinfection by-products formed by chlorination

- Subject to chlorination, MCLR was transformed into 5 types of MCLR-DBPs.
- MS/MS analysis indicated that the conjugated diene in Adda was a major target site.
- Most MCLR-DBPs had lower toxicity on protein phosphatase 1 than MCLR.
- MCLR-DBPs still possessed certain biological toxicity and environmental risk.
- The secondary pollution of MCLR-DBPs in drinking water deserves further attention.