کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5904549 | 1158009 | 2012 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Fish oil increases blood flow in the ileum during chronic feeding in rats
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کلمات کلیدی
HSDGastrointestinal blood flowGALTIEDl-arginine - آرژینین الPolyunsaturated fatty acids - اسید چرب اشباع نشدهPUFA - اسید چرب چند غیراشباعN-3 fatty acids - اسیدهای چرب N-3Immunonutrition - ایمنیanalysis of variance - تحلیل واریانسANOVA - تحلیل واریانس Analysis of variancehonestly significant difference - تفاوت صادقانه قابل توجه استFish oil - روغن ماهیcontrol diet - رژیم غذایی کنترلBreast milk - شیر مادرHeart rate - ضربان قلبmean arterial pressure - فشار متوسط شریانیRats - موش صحراییmap - نقشهNucleotides - نوکلئوتیدNitric oxide - نیتریک اکسید
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
علوم غدد
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Benefits of enteral feeding with immune-enhancing diets (IEDs) depend on route, timing, and composition. We hypothesized that chronic enteral feeding with certain individual immunonutrients would enhance gastrointestinal blood flow. Male rats were fed a standard enteral diet supplemented with immunonutrients for 5 days before study. Groups were (1) standard rat chow, (2) liquid control diet (CD) alone (CD), (3) CD + fish oil, (4) CD + l-arginine, and (5) CD + RNA fragments. Whole organ blood flow distribution was measured by colorimetric microsphere technique in antrum, small intestine (in thirds), colon, liver, spleen, pancreas, and kidneys. Chronic feeding for 5 days with CD + fish oil increased blood flow in the distal third of the small intestine compared with CD alone, whereas feeding with CD + l-arginine decreased blood flow in the small intestine (all segments) compared with CD alone. Acute gavage of CD + l-arginine or CD + fish oil increased blood flow in the proximal and middle third of the small intestine compared with CD alone. Control diet + RNA increased blood flow in the proximal small intestine compared with CD alone. These findings support prior acute feeding studies with CD, CD + individual immunonutrients, or IED. Our current data suggest that blood flow benefits associated with fish oil persist during chronic feeding in rats. Enhanced gastrointestinal perfusion might partially explain the benefits of early enteral feeding with IEDs not seen with regular enteral diets and parenteral immunonutrient delivery.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Nutrition Research - Volume 32, Issue 11, November 2012, Pages 837-843
Journal: Nutrition Research - Volume 32, Issue 11, November 2012, Pages 837-843
نویسندگان
Ryan T. Hurt, R. Neal Garrison, Brian M. Derhake, Paul J. Matheson,