ACR-26: A novel nicotinic receptor subunit of parasitic nematodes

► We identified a novel nicotinic receptor subunit, acr-26. ► The acr-26 gene is present in a wide range of parasitic species, but not Caenorhabditis elegans. ► ACR-26 is expressed on muscle cells in the head region of Ascaris suum. ► ACR-26 forms homomeric receptors that respond to acetylcholine and nicotine.