Colloidal stability and physicochemical characterization of bombesin conjugated biodegradable nanoparticles

- Bombesin grafted biodegradable nanoparticles (BPNP) were prepared and optimized.
- Effect of time, medium and electrolytes concentration on stability was evaluated.
- Changes in optical density and particle size were used as stability indicators.
- Critical flocculation concentration was determined by calculating Fuchs factor.
- BPNP were found to be more stable than unconjugated nanoparticles.