Biofunctional mesoporous silica nanoparticles for magnetically oriented target and pH-responsive controlled release of ibuprofen

► A dual-functional drug delivery system with magnetic targeting and pH-response. ► The materials exhibited highly ordered mesostructure, superior magnetic property, etc. ► Eudragit-S100 as a pH-sensitive coating. ► The systems have excellent drug release in alkaline conditions. ► The systems may show a promising biomedical application.