Lesion Explorer: A comprehensive segmentation and parcellation package to obtain regional volumetrics for subcortical hyperintensities and intracranial tissue

►Lesion Explorer segmentation and parcellation of structural MRI show high reliability. ►LE allows for segmentation of periventricular, deep white, VR, and lacunar subtypes. ►LE provides comprehensive volumetric profiles to examine subcortical vasculopathy.