کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6352939 1622569 2014 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Associations between personal exposure to air pollutants and lung function tests and cardiovascular indices among children with asthma living near an industrial complex and petroleum refineries
ترجمه فارسی عنوان
ارتباط بین قرار گرفتن در معرض آلودگی هوا و آزمایش های ریه و شاخص های قلبی-عروقی در کودکان مبتلا به آسم در نزدیکی یک مجتمع صنعتی و پالایشگاه های نفتی
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم محیط زیست بهداشت، سم شناسی و جهش زایی
چکیده انگلیسی


- We assessed cardio-pulmonary functions of 72 children with asthma over 10 days.
- Personal exposure to air pollutants levels was measured.
- No consistent association was observed between health outcomes and personal exposures.
- A tendency for a small lung function decrease with aromatic hydrocarbons was noted.
- Effects are difficult to detect over 10 consecutive days at low exposure levels.

ObjectiveThe acute cardiorespiratory effects of air quality among children living in areas with considerable heavy industry have not been well investigated. We conducted a panel study of children with asthma living in proximity to an industrial complex housing two refineries in Montreal, Quebec, in order to assess associations between their personal daily exposure to air pollutants and changes in pulmonary function and selected indicators of cardiovascular health.MethodsSeventy-two children with asthma age 7-12 years in 2009-2010 participated in this panel study for a period of 10 consecutive days. They carried a small backpack for personal monitoring of sulphur dioxide (SO2), benzene, fine particles (PM2.5), nitrogen dioxide (NO2) and polycyclic aromatic hydrocarbons (PAHs) and underwent daily spirometry and cardiovascular testing (blood pressure, pulse rate and oxygen saturation). To estimate these associations, we used mixed regression models, adjusting for within-subject serial correlation, and for the effects of a number of personal and environmental variables (e.g., medication use, ethnicity, temperature).ResultsChildren with asthma involved in the study had relatively good pulmonary function test results (mean FEV1 compared to standard values: 89.8%, mean FVC: 97.6%, mean FEF25-75: 76.3%). Median diastolic, systolic blood pressures and oxygen saturation were 60/94 mm Hg and 99%, respectively. Median personal concentrations of pollutants were NO2, 5.5 ppb; benzene, 2.1 µg/m3; PM2.5, 5.7 µg/m3; and total PAH, 130 µg/m3. Most personal concentrations of SO2 were below the level of detection. No consistent associations were observed between cardio-pulmonary indices and personal exposure to PM2.5, NO2 and benzene, although there was a suggestion for a small decrease in respiratory function with total concentrations of PAHs (e.g., adjusted association with FVC: −9.9 ml per interquartile range 95%CI: −23.4, 3.7).ConclusionsThis study suggests that at low daily average levels of exposure to industrial emissions, effects on pulmonary and cardiovascular functions in children with asthma may be difficult to detect over 10 consecutive days.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Environmental Research - Volume 132, July 2014, Pages 38-45
نویسندگان
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