کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
652792 1457441 2006 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Integrated microthermoelectric cooler for microfluidic channels
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی جریان سیال و فرایندهای انتقال
پیش نمایش صفحه اول مقاله
Integrated microthermoelectric cooler for microfluidic channels
چکیده انگلیسی

Precise fluid temperature control in microfluidic channels is a requirement for many lab-on-a-chip and microreactor devices, especially in biotechnology where most processes are highly temperature sensitive. We demonstrate the concept of a microthermoelectric cooler integrated into a microfluidic channel in order to give rapid and localised fluid cooling. The key aspect of this concept is the use of a second imbedded microfluidic channel that is used as a miniature heat sink. An analytical thermal model has been derived that couples thermoelectric effects with fluid heat-transfer rates from both the hot and cold connections. Using this model, the effect on cooling performance of varying the thermal resistance between the hot and cold connections and the fluid has been quantified, as well as the effect of substrate thermal conductivity. If the substrate thermal conductivity is too high, heat leakage renders the thermoelectric cooler ineffective. The optimum electrical current for cooling has been shown to be a function of the thermal resistance of the heat sink. For thermoelectric coolers there is competition between temperature reduction and cooling power. Using this fact, based on the final fluid temperature required, we have calculated the maximum flow rate that will achieve this. Finally, a prototype integrated microthermoelectric cooler has been fabricated and tested.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Experimental Thermal and Fluid Science - Volume 30, Issue 8, August 2006, Pages 821–828
نویسندگان
, , ,